TMOD3/CYP19A1 Fusion Gene

A fusion gene that results from a chromosomal inversion within 15q21.2-q21.3 and places the promoter for the TMOD3 gene near the 5' end of the CYP19A1 gene. This fused gene causes increased expression of the CYP19A1 gene and is associated with aromatase excess syndrome. (NCI Thesaurus)

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TMOD3 wt Allele

Human TMOD3 wild-type allele is located within 15q21.1-q21.2 and is approximately 83 kb in length. This allele, which encodes tropomodulin-3 protein, plays…

TMOD3 Gene

This gene is involved in the stabilization of actin filaments.

Tmin

The time of minimum concentration sampled during a dosing interval.

TmHMM Algorithm

A computer algorithm that predicts trans-membrane helices based on the hidden Markov model.

TMEM216 wt Allele

Human TMEM216 wild-type allele is located in the vicinity of 11q13.1 and is approximately 7 kb in length. This allele, which encodes…

TMEM216 Gene

This gene is involved in ciliogenesis.