TMPRSS2/ERG Fusion Gene

A fusion gene that results from a genetic translocation event which fuses the 5' end of the androgen-regulated TMPRRSS2 gene with the entire coding region of the ERG gene. The androgen-dependent expression of this fusion gene results in overexpression of ERG activity. (NCI Thesaurus)

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TMPRSS2 wt Allele

Human TMPRSS2 wild-type allele is located in the vicinity of 21q22.3 and is approximately 51 kb in length. This allele, which encodes…

TMPRSS2 Gene

This gene plays a role in the activation of pathway signaling.

TMPO wt Allele

Human TMPO wild-type allele is located in the vicinity of 12q22 and is approximately 34 kb in length. This allele, which encodes…

TMPO Gene Product

A protein encoded by the TMPO gene.

TMPO Gene

This gene plays a role in nuclear structure.

TMOD3/CYP19A1 Fusion Gene

A fusion gene that results from a chromosomal inversion within 15q21.2-q21.3 and places the promoter for the TMOD3 gene near the 5'…