TNFRSF11B wt Allele

Human TNFRSF11B wild-type allele is located in the vicinity of 8q24 and is approximately 29 kb in length. This allele, which encodes tumor necrosis factor receptor superfamily member 11B protein, plays a role in bone homeostasis through the mediation of osteoclast apoptosis. Deletions and mutations in the gene are associated with juvenile Paget disease of the bone. (NCI Thesaurus)

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TNFRSF11B Gene

This gene is involved in the negative regulation of bone resorption.

TNFRSF11A wt Allele

HumanTNFRSF11A wt allele is located in the vicinity of 18q22.1 and is approximately 61 kb in length. This allele, which encodes tumor…

TNFRSF11A Gene

This gene plays a role in the regulation of bone resorption.

TNFRSF10C wt Allele

Human TNFRSF10C wild-type allele is located within 8p22-p21 and is approximately 48 kb in length. This allele, which encodes tumor necrosis factor…

TNFRSF10C Gene

This gene is involved in both ligand binding and the negative regulation of apoptotic signaling.

TNFRSF10B wt Allele

Human TNFRSF10B wild-type allele is located within 8p22-p21 and is approximately 49 kb in length. This allele, which encodes tumor necrosis factor…