TNFSF10 wt Allele

Definition 1

Human TNFSF10 wild-type allele is located within 3q26 and is approximately 18 kb in length. This allele, which encodes tumor necrosis factor ligand superfamily member 10 protein, is involved in the induction and modulation of apoptosis. (NCI Thesaurus)

Definition 2

A cell protein that can attach to certain molecules in some cancer cells and may kill the cells. Apo-2L is being studied in the treatment of cancer. (NCI Dictionary)

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A protein encoded by the TNFRSF8 gene.

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This gene is involved in pro-apoptotic regulation via the NF-kappaB signal transduction pathway.