Health / Medical Topics

    TOP2A Gene

    This gene plays a role in DNA replication, chromosome recombination and the regulation of DNA topology during transcription. (NCI Thesaurus)




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    Human TOP1 wild-type allele is located within 20q12-q13.1 and is approximately 96 kb in length. This allele, which encodes DNA topoisomerase 1…
    This gene is involved in the regulation of both DNA topology and transcription.
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