TOPBP1 wt Allele

Human TOPBP1 wild-type allele is located in the vicinity of 3q22.1 and is approximately 61 kb in length. This allele, which encodes DNA topoisomerase 2-binding protein 1, is involved in DNA double-strand breaks, and map play a role in DNA damage and replication checkpoint controls. (NCI Thesaurus)

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TOPBP1 Gene

This gene is involved in DNA replication and apoptosis regulation.

TOP3B wt Allele

Human TOP3B wild-type allele is located in the vicinity of 22q11.22 and is approximately 26 kb in length. This allele, which encodes…

TOP3B Gene

This gene is involved in DNA recombination, cellular aging and the maintenance of genome integrity.

TOP3A wt Allele

Human TOP3A wild-type allele is located within 17p12-p11.2 and is approximately 41 kb in length. This allele, which encodes DNA topoisomerase 3-alpha…

TOP3A Gene

This gene plays a role in the regulation of DNA topology and recombination in somatic cells.

TOP2B wt Allele

Human TOP2B wild-type allele is located within 3p24 and is approximately 66 kb in length. This allele, which encodes DNA topoisomerase 2-beta…