Topical Menthol Cream

A topical cream containing menthol that both causes a localized cooling sensation and has analgesic activities. Upon topical application, menthol acts on the cold-sensitive transient receptor potential cation channel subfamily M member 8 (TMPR8), which provides a cooling sensation. This treatment also provides an analgesic effect through the activation of the inhibitory Group II/III metabotropic glutamate receptors (mGluRs). This may decrease neuropathic pain from chemotherapy. In addition, the topical application of menthol causes vasodilation. (NCI Thesaurus)

YOU MAY ALSO LIKE

Topical Lotion Dosage Form

A lotion intended for administration to a body surface.

Topical Gemcitabine Hydrochloride

A topical preparation of gemcitabine hydrochloride with antineoplastic activity. Gemcitabine, an analogue of the antimetabolite nucleoside deoxycytidine, is converted intracellularly to the…

Topical Gel Dosage Form

A gel intended for administration to a body surface.

Topical Foam Dosage Form

A foam intended for administration to a body surface.

Topical Dosage Form

A substance intended for administration to a body surface.

Topical Cream Dosage Form

A cream intended for administration to a body surface.