Health / Medical Topics

    Total Clearance Observed by Fraction Dose Normalized by Surface Area

    Definition 1

    The observed total body clearance for extravascular administration based on the fraction of dose absorbed and divided by the surface area. (NCI Thesaurus)

    Definition 2

    The total body clearance for extravascular administration divided by the fraction of dose absorbed, calculated using the observed value of the last non-zero concentration, divided by the surface area. (NCI Thesaurus/CDISC)




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