| Health / Medical Topics |
Total Colonic Aganglionosis
The severe form of Hirschsprung disease, this is characterized by a complete lack of nerve cells in the large intestine, and often a partial lack in the small intestine. The bowel is not stimulated without innervation and obstruction ensues. Surgical intervention is necessary. (NCI Thesaurus)
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Surgical removal of the entire colon.
The predicted total body clearance for intravascular administration divided by the weight.
The predicted total body clearance for intravascular administration divided by the surface area.
The predicted total body clearance for intravascular administration divided by the dose.
The predicted total body clearance for intravascular administration divided by the body mass index.
The predicted total body clearance for extravascular administration based on the fraction of dose absorbed and divided by the weight.
