Health / Medical Topics

    Toxic Shock Syndrome Toxin-1

    Staphylococcal toxic shock syndrome toxin 1. A superantigen with the potential to suppress plasma cell differentiation and antibody responsiveness. Potent pyrogen, induces T lymphocyte proliferation, requiring interleukin 1 release from macrophages, suppresses immunoglobulin production, enhances endotoxin shock, and enhances hypersensitivity skin reactions. Causes staphylococcal toxic shock syndrome (TSS). (NCI Thesaurus)




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