TP63 wt Allele

Human TP63 wild-type allele is located in the vicinity of 3q28 and is approximately 266 kb in length. This allele, which encodes tumor protein 63, is involved in the modulation of both apical ectoderm development and gene transcription. Mutation of the gene is associated with cervical, colon, head and neck, lung and ovarian cancers and numerous congenital disorders caused by aberrant ectodermal development and differentiation. (NCI Thesaurus)

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TP63 Gene

This gene plays a role in both transcriptional regulation and limb development.

TP53INP1 wt Allele

Human TP53INP1 wild-type allele is located in the vicinity of 8q22 and is approximately 23 kb in length. This allele, which encodes…

TP53INP1 Gene

This gene plays a role in the regulation of apoptosis.

TP53BP2 wt Allele

Human TP53BP2 wild-type allele is located in the vicinity of 1q42.1 and is approximately 66 kb in length. This allele, which encodes…

TP53BP2 Gene

This gene plays an inhibitory role in G2/M cell cycle progression and stimulates the transactivation of pro-apoptotic genes.

TP53BP1 wt Allele

Human TP53BP1 wild-type allele is located within 15q15-q21 and is approximately 103 kb in length. This allele, which encodes tumor suppressor p53-binding…