TPM1 wt Allele

Human TPM1 wild-type allele is located in the vicinity of 15q22.1 and is approximately 29 kb in length. This allele, which encodes tropomyosin alpha-1 chain protein, is involved in the regulation of muscle contraction. Mutation of the gene is associated with left ventricular non-compaction 9 and cardiomyopathy types familial hypertrophic 3 and dilated 1Y. (NCI Thesaurus)

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TPM1 Gene

This gene plays a role in muscle contraction.

TPI1 wt Allele

Human TPI1 wild-type allele is located in the vicinity of 12p13.31 and is approximately 4 kb in length. This allele, which encodes…

TPI1 Gene

This gene plays a role in glycolysis and gluconeogenesis.

TPH1 wt Allele

Human TPH1 wild-type allele is located within 11p15.3-p14 and is approximately 25 kb in length. This allele, which encodes tryptophan 5-hydroxylase 1…

TPH1 Gene

This gene plays a role in amino acid metabolism.

TPH Inhibitor LX1606

An orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor prodrug with potential antiserotonergic activity. Upon administration, TPH inhibitor LX1606 is converted to its…