TPM3/ALK Fusion Gene

A fusion gene that results from a chromosomal translocation t(1;2)(q25;p23) which fuses most of the coding sequence of the TPM3 gene to the last 10 exons of the ALK gene. This rearrangement is associated with anaplastic large cell lymphoma and inflammatory myofibroblastic tumor. (NCI Thesaurus)

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TPM3 wt Allele

Human TPM3 wild-type allele is located in the vicinity of 1q21.2 and is approximately 39 kb in length. This allele, which encodes…

TPM3 Gene

This gene plays a role in muscle contraction.

TPM1 wt Allele

Human TPM1 wild-type allele is located in the vicinity of 15q22.1 and is approximately 29 kb in length. This allele, which encodes…

TPM1 Gene

This gene plays a role in muscle contraction.

TPI1 wt Allele

Human TPI1 wild-type allele is located in the vicinity of 12p13.31 and is approximately 4 kb in length. This allele, which encodes…

TPI1 Gene

This gene plays a role in glycolysis and gluconeogenesis.