TPM3 wt Allele

Human TPM3 wild-type allele is located in the vicinity of 1q21.2 and is approximately 39 kb in length. This allele, which encodes tropomyosin alpha-3 chain protein, is involved in the mediation of muscle filament movement. Mutation of the gene is associated with nemaline myopathy type 1 and thyroid papillary carcinoma. A chromosomal rearrangement affecting this gene and the NTRK gene is associated with thyroid papillary carcinoma. A chromosomal translocation t(1;2)(q25;p23) of the gene and the ALK gene is associated with rare cases of both anaplastic large cell lymphoma and inflammatory myofibroblastic tumors. (NCI Thesaurus)

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TPM3 Gene

This gene plays a role in muscle contraction.

TPM1 wt Allele

Human TPM1 wild-type allele is located in the vicinity of 15q22.1 and is approximately 29 kb in length. This allele, which encodes…

TPM1 Gene

This gene plays a role in muscle contraction.

TPI1 wt Allele

Human TPI1 wild-type allele is located in the vicinity of 12p13.31 and is approximately 4 kb in length. This allele, which encodes…

TPI1 Gene

This gene plays a role in glycolysis and gluconeogenesis.

TPH1 wt Allele

Human TPH1 wild-type allele is located within 11p15.3-p14 and is approximately 25 kb in length. This allele, which encodes tryptophan 5-hydroxylase 1…