Health / Medical Topics

    Transaminase

    Pronunciation

    Definition 1

    A type of enzyme that causes the transfer of a chemical substance called an amino group from one molecule to another. Transaminases are involved in many processes in the body, such as making amino acids. (NCI Dictionary)

    Definition 2

    Transaminases are a sub-subclass of mostly pyridoxal phosphate-dependent transferase enzymes that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Mediating conversion of major intermediate metabolites and reversible transamination, Transaminases are often involved in cellular nitrogen metabolism, amino acid metabolism, gluconeogenesis and in the urea and tricarboxylic acid cycles. (NCI Thesaurus)




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