Health / Medical Topics |
Transforming Growth Factor Alpha
Transforming growth factor alpha (TGFA) stimulates the growth and proliferation of cells, and its overexpression has been correlated with patient survival in a variety of tumors, including squamous carcinoma of the esophagus. In esophageal adenocarcinoma patients who received high-dose radiation and chemotherapy those with tumors that persistently expressed or that increased TGFA expression had a worse prognosis. (from Int J Radiat Oncol Biol Phys. 1995;31:567-9) (NCI Thesaurus)
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