| Health / Medical Topics |
Transgenic Mouse
Definition 1
A mouse whose genome has been altered by the inclusion of foreign genetic material. The technique involves microinjection of foreign DNA fragments into the nucleus of a fertilized egg. The inserted gene becomes integrated into every cell and tissue of the mouse. (NCI Thesaurus)
Definition 2
Laboratory mice that have been produced from a genetically manipulated egg or embryo. The technique involves microinjection of DNA fragments from another species into the nucleus of the fertilized egg. (NLM, Medical Subject Headings)
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Indicates if a transgene or targeted modification is done conditionally (time or tissue specific).
