Library / English Dictionary

TRANSLOCATE

Pronunciation (US):

(GB):

 I. (verb) 

Sense 1

Meaning:

Move from one place to another, especially of wild animals

Example:

The endangered turtles were translocated to a safe environment

Classified under:

Verbs of buying, selling, owning

Hypernyms (to "translocate" is one way to...):

transfer (move from one place to another)

Sentence frame:

Somebody ----s something

Sense 2

Meaning:

Transfer (a chromosomal segment) to a new position

Classified under:

Verbs of buying, selling, owning

Hypernyms (to "translocate" is one way to...):

shift; transfer (move around)

Sentence frame:

Somebody ----s something

Derivation:

translocation ((genetics) an exchange of chromosome parts)

Credits

 Context examples: 

NFATC, the Dorsal/Rel family cytosolic component of NFAT, is translocated to the nucleus following TCR-induced PKC stimulation and calmodulin-dependent calcineurin-mediated dephosphorylation.

(NF-AT, NCI Thesaurus)

Erk5 does not directly phosphorylate CREB, but translocates into the nucleus and phosphorylates the kinase Rsk, which phosphorylates CREB in turn.

(Neuronal Survival Pathway, NCI Thesaurus/BIOCARTA)

Steroid receptors are cytoplasmic carriers that translocate to the nucleus upon ligand binding and regulate the expression of specific target genes.

(Cytoplasmic Receptor, NCI Thesaurus)

Upon oral administration, dienogest binds intracellular progesterone receptors which then translocate to the nucleus where the drug-receptor complex interacts with progesterone response elements, thus altering the expression of target genes.

(Dienogest, NCI Thesaurus)

In Gram-positive bacteria, secreted proteins are commonly translocated across the single membrane by the Sec pathway or the two-arginine (Tat) pathway.

(Bacterial Secretion System Pathway, NCI Thesaurus/KEGG)

Cytosolic Nrf2 is phosphorylated and translocates into the nucleus in response to protein kinase C activation and Map kinase pathways.

(Oxidative Stress Pathway, NCI Thesaurus/BIOCARTA)

The ABL2 gene is translocated in acute myelogenous leukemia.

(ABL2 wt Allele, NCI Thesaurus)

Once inside the neuron, the light chain is translocated across the vesicular membrane to act as a protease on cytoplasmic substrates.

(Botulin Pathway, NCI Thesaurus/BIOCARTA)

Xp11 translocated renal carcinomas are associated with a translocation t(X;17)(p11;q23) of this gene and the TFE3 gene.

(CLTC wt Allele, NCI Thesaurus)

Activated NFKB translocates to the nucleus, binds at kappa-B DNA binding motifs, and regulates transcription of target genes.

(Conserved Helix-Loop-Helix Ubiquitous Kinase, NCI Thesaurus)