Transplant Conditioning

Definition 1

Administration of high doses of chemotherapy or radiation therapy, as well as immunosuppressive therapy, to a transplant recipient prior to a bone marrow or hematopoietic stem cell transplant. Conditioning destroys the patient's abnormal blood cells or cancer, as well as slows the patient's immune response against the donor bone marrow (graft rejection). (NCI Thesaurus)

Definition 2

The treatments used to prepare a patient for stem cell transplantation (a procedure in which a person receives blood stem cells, which make any type of blood cell). A conditioning regimen may include chemotherapy, monoclonal antibody therapy, and radiation to the entire body. It helps make room in the patient's bone marrow for new blood stem cells to grow, helps prevent the patient's body from rejecting the transplanted cells, and helps kill any cancer cells that are in the body. (NCI Dictionary)

YOU MAY ALSO LIKE

Transplacental Route of Administration

Administration of a drug to an embryo in utero via systemic administration of the substance to the pregnant mother. Drugs cross the…

Transplacental Carcinogenesis

Studies of the mechanisms of induction of cancer in an individual by in utero exposure to a carcinogen.

Transperineal template-guided prostate mapping biopsy

A procedure being studied in the diagnosis of prostate cancer and in planning prostate cancer treatment. Ultrasound is used to create a…

Transperineal biopsy

A procedure in which a sample of tissue is removed from the prostate for examination under a microscope. The sample is removed…

Transparent

Allowing the passage of light such that images can be seen through with clarity.

Transoral robotic surgery

Surgery in which a robot with arms is used to remove cancer from hard-to-reach areas of the mouth and throat. Cameras…