Health / Medical Topics |
Tretinoin Liposome
An intravenous formulation of tretinoin (vitamin A acid or all-trans retinoic acid) encased in liposomes. Tretinoin is a naturally occurring retinoic acid agent that binds to and activates retinoic acid receptors (RAR), effecting changes in gene expression that lead to cell differentiation, decreased cell proliferation, and inhibition of carcinogenesis. This agent also inhibits telomerase, leading to telomere shortening and eventual apoptosis of certain tumor cell types. Liposome encapsulation extends the half-life of intravenously administered tretinoin. (NCI Thesaurus)
YOU MAY ALSO LIKE
A nutrient that the body needs in small amounts to function and stay healthy. Tretinoin is made in the body from vitamin…
A prodrug of a bifunctional alkylating, dinitrobenzamide derivative with antineoplastic activity. Tretazicar can be activated by the human enzyme quinone oxidoreductase 2…
Human TRERF1 wild-type allele is located within 6p21.1-p12.1 and is approximately 227 kb in length. This allele, which encodes transcriptional-regulating factor 1…
This gene is involved in tumorigenesis.
A sexually transmitted infection caused by the Gram-negative spirochete Treponema pallidum. It is manifested as syphilis.
A subspecies of Treponema pallidum; an anaerobic, Gram indeterminate, spiral shaped bacteria assigned to the phylum Spirochaetes. This subspecies is motile and…