Tribe

Tribbles homolog 2 (343 aa, ~39 kDa) is encoded by the human TRIB2 gene. This protein is involved in the modulation of…

Human TRIB2 wild-type allele is located in the vicinity of 2p24.3 and is approximately 26 kb in length. This allele, which encodes…

This gene is involved in the regulation of mitogen activated protein kinase activity.

A triazolobenzodiazepinederivative with sedative-hypnotic property. Triazolam interacts directly with a specific site on the gamma-aminobutyric acid (GABA)-A-chloride-ionophore receptor complex located on the…

An aziridinylbenzoquinone-based alkylating agent with potential antineoplastic activity. The alkylating group in triaziquone becomes activated upon reduction of quinone to the hydroquinone…

A synthetic dihydrotriazine derivative with antineoplastic properties. As an antifolate agent related to methotrexate (MTX), triazinate inhibits the enzyme dihydrofolate reductase…