Trimethadione

A dione-type anticonvulsant with antiepileptic activity. Trimethadione reduces T-type calcium currents in thalamic neurons, thereby stabilizing neuronal membranes, raising the threshold for repetitive activities in the thalamus and inhibiting corticothalamic transmission. This decreases the abnormal thalamocortical rhythmicity, which is thought to underlie the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. (NCI Thesaurus)

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A period of three months; especially one of the three three-month periods into which human pregnancy is divided.

Trimelamol

A synthetic derivative of trimethylmelamine with antineoplastic properties. An analogue of siderophores (microbial iron chelators), trimelamol induces the formation of a…

TRIM5 wt Allele

Human TRIM5 wild-type allele is located in the vicinity of 11p15 and is approximately 275 kb in length. This allele, which encodes…

TRIM5 Gene

This gene plays a role in viral infection response.

TRIM36 wt Allele

Human TRIM36 wild-type allele is located in the vicinity of 5q22.3 and is approximately 56 kb in length. This allele, which encodes…

TRIM36 Gene

This gene is involved in protein modification.