Health / Medical Topics

    Trk inhibitor LOXO-101

    Pronunciation

    A substance that blocks a protein called Trk, which is involved in cell signaling and growth. Trk may be found in a mutated (changed) form or at high levels in some types of cancer cells. Blocking this protein may help keep cancer cells from growing and may kill them. Trk inhibitor LOXO-101 is being studied in the treatment of some types of cancer. It is a type of tyrosine kinase inhibitor and a type of targeted therapy. Also called LOXO-101. (NCI Dictionary)




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