| Health / Medical Topics |
Troglitazone
An orally-active thiazolidinedione with antidiabetic and hepatotoxic properties and potential antineoplastic activity. Troglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. (NCI Thesaurus)
YOU MAY ALSO LIKE
An orally bioavailable oxazaphosphorine prodrug with antineoplastic activity. Trofosfamide (TFF) is metabolized predominantly to the cyclophosphamide analogue ifosfamide (IFO), which is then…
A non-neoplastic or neoplastic disorder affecting the trochlear nerve (IVth cranial nerve).
The cranial nerve that controls the superior oblique muscle of the eye.
A dosing unit equal to the amount of active ingredient(s) contained in a troche.
A solid discoid composed of active and/or inert ingredient(s) in a suitably flavored base, that dissolves when sucked in the mouth. …
A bony protrusion on the femoral bone to which muscles are attached.
