Health / Medical Topics

    Tumor Infiltrating Lymphocytes-N2-Transduced

    A preparation of lymphocytes harvested from a patient and genetically modified ex vivo for use in gene therapy for the patient's cancer. Ex vivo, the lymphocytes are transduced with the N2 retroviral vector, which is modified to express a gene whose protein product either kills tumor cells or elicits specific anti-tumor immunity. Genetically modified lymphocytes are infused back into the patient from whom they were harvested, locate to the tumor site, and express the candidate protein that kills tumor cells or stimulates host anti-tumor immunity. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A white blood cell that has left the bloodstream and migrated into a tumor.
    Interactions of the immune system and tumor cells
    Mechanisms that prevent immune detection and elimination of tumor cells
    A domain that represents the data that uniquely identifies tumors.
    A diagnostic procedure to localize and characterize a tumor.
    A morphologic classification system of malignant tumors, usually relating to disease progression and clinical outcome. It is based upon the presence…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact