Tumor Necrosis Factor-Beta

Human tumor necrosis factor-beta protein (205 aa, 22 kDa precursor) is encoded by the human lymphotoxin alpha (LTA) gene. This soluble glycoprotein is released by antigen- or mitogen-activated lymphocytes and is a cytotoxic to other cells. It is involved in allergies and chronic inflammatory diseases. (NCI Thesaurus)

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Any therapeutic or preventive procedure that involves inhibition of the production or activity of a Tumor Necrosis Factor. This process may result…

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Any process which promotes expression of tumor necrosis factors, their subsequent secretion, binding to cognate receptors and intracellular signaling, and results in…

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Tumor necrosis factor receptor superfamily member 6 (335 aa, 38 kD) is a cell fate protein that is encoded by the human…

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A 70-kDa high-affinity cell surface receptor for tumor necrosis factor.

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TNFR1 is a 55 kD high-affinity cell surface receptor for tumor necrosis factor. Activated receptor interacts with death domains of TRADD…