Health / Medical Topics

    tumor necrosis factor receptor superfamily member 10A

    Pronunciation

    Definition 1

    A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or activity of tumor necrosis factor receptor superfamily member 10A on cancer cells may kill more cells. Also called death receptor 4, DR4, TRAIL receptor 1, and TRAIL-R1. (NCI Dictionary)

    Definition 2

    Tumor necrosis factor receptor superfamily member 10A (468 aa, 50 kD) is a cell fate protein that is encoded by the human TNFRSF10A gene and may have roles in induction of apoptosis. (NCI Thesaurus)




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