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Tumor Necrosis Factor Receptor Superfamily Member 4
Definition 1
Tumor necrosis factor receptor superfamily member 4 (277 aa, ~29 kDa) is encoded by the human TNFRSF4 gene. This protein plays a role in signal transduction pathways that mediate apoptosis inhibition and inflammatory responses. (NCI Thesaurus)
Definition 2
A protein being studied in the treatment of cancer. Substances that attach to OX-40 on the surface of T cells (a type of white blood cell) may help the T cells grow and kill more cancer cells. OX-40 is a type of tumor necrosis factor (TNF) receptor. (NCI Dictionary)
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