Health / Medical Topics

    Tyrphostin Compound

    Definition 1

    Any of a class of synthetic protein tyrosine kinase inhibitors based on the structure of Erbstatin, a compound initially isolated from Streptomyces MH435-hF3 that inhibits the autophosphorylation of the receptor for epidermal growth factor. (NCI Thesaurus)

    Definition 2

    A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor function. (NLM, Medical Subject Headings)




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