Library / English Dictionary |
ULTIMATELY
Pronunciation (US): | (GB): |
I. (adverb)
Sense 1
Meaning:
As the end result of a succession or process
Example:
at long last the winter was over
Synonyms:
at last; at long last; finally; in the end; ultimately
Classified under:
Pertainym:
ultimate (being the last or concluding element of a series)
Context examples:
This ultimately inhibits the expression of genes that regulate prostate cancer cell proliferation and may lead to an inhibition of cell growth in AR-expressing tumor cells.
(Androgen Receptor Antagonist ARN-509, NCI Thesaurus)
This leads to an inhibition of GM-CSF-mediated signaling and ultimately prevents inflammation.
(Namilumab, NCI Thesaurus)
Carubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis.
(Carubicin Hydrochloride, NCI Thesaurus)
DNA crosslinks and adducts ultimately lead to the induction of apoptosis.
(Platinum Compound, NCI Thesaurus)
As a result, this agent causes cell cycle arrest in S-phase, and ultimately inhibits tumor cell proliferation
(Pelitrexol, NCI Thesaurus)
Ultimately this induces apoptosis and reduces tumor cell proliferation.
(p38 MAPK Inhibitor LY2228820 Dimesylate, NCI Thesaurus)
This leads to an inhibition of DNA replication and ultimately cell death.
(Palifosfamide Tromethamine, NCI Thesaurus)
The activation effects of the phenobarbital-receptor-ionophore complex include increased frequency of chloride channel openings, membrane hyperpolarization and ultimately synaptic inhibition and decreased neuronal excitability.
(Phenobarbital, NCI Thesaurus)
However, this agent interferes with cell wall synthesis, thereby causing weakening of the cell wall and ultimately cell lysis.
(Antibiotic SQ109, NCI Thesaurus)
Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cancer cell growth.
(Antineoplastic Alkylating Agent, NCI Thesaurus)