| Health / Medical Topics |
ULvWF Multimer-targeting Agent ARC1779
An optimized, second-generation, PEGylated aptamer with antithrombotic property. ULvWF multimer-targeting agent ARC1779 blocks the binding of von Willebrand factor (vWF), via the A1 domain, and ultra-large vWF multimers to platelets, as well as interferes with the binding of platelet receptor glycoprotein Ib, thus reducing platelet adhesion, aggregation and thrombus growth in arterial beds. Unlike other antiplatelet agents, this aptamer can be readily reversed by binding to a complementary sequence of oligonucleotides, and may therefore offer potential therapeutic benefit in surgery. (NCI Thesaurus)
YOU MAY ALSO LIKE
A form of radiation used in the treatment of cancer.
The field of science that studies the biological effects of ultraviolet radiation.
Invisible rays that are part of the energy that comes from the sun. Ultraviolet radiation that reaches the Earth's surface is made…
The study and photographing of microscope specimens in ultraviolet light. It is particularly useful when all parts of the specimen viewed are…
A sterilization process that uses short wavelength radiation to kill microorganisms. This process is used primarily in medical sanitation and sterile work…
Invisible rays that are part of the energy that comes from the sun. Most ultraviolet C radiation from the sun is blocked…
