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Vascular endothelial growth factor trap
Pronunciation
A drug used with other drugs to treat colorectal cancer that has spread to other parts of the body and has not gotten better with chemotherapy. It is also being studied in the treatment of other types of cancer. Vascular endothelial growth factor trap blocks the action of a protein called vascular endothelial growth factor (VEGF) and may prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent. Also called VEGF Trap, Zaltrap, and ziv-aflibercept. (NCI Dictionary)
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A substance that blocks an enzyme needed to form blood vessels. Also called VEGFR tyrosine kinase inhibitor.
Vascular endothelial growth factor receptor 3 (1363 aa, ~153 kDa) is encoded by the human FLT4 gene. This protein is involved in…
Vascular endothelial growth factor receptor 2 (1356 aa, ~152 kDa) is encoded by the human KDR gene. This protein is involved in…
Vascular endothelial growth factor receptor 1 (1338 aa, ~151 kDa) is encoded by the human FLT1 gene. This protein is involved in…
There are three signaling VEGF receptors. The VEGF family members PIGF and VEGF-B with exclusive binding capacities to the VEGFR-1 can influence…
The determination of the amount of vascular epithelial growth factor present in a sample.
