Vatalanib

Pronunciation

Definition 1

A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called protein tyrosine kinase inhibitors and VEGF receptor kinase inhibitors. Also called PTK787/ZK 222584. (NCI Dictionary)

Definition 2

An orally bioavailable anilinophthalazine with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms. (NCI Thesaurus)

YOU MAY ALSO LIKE

Vastus Lateralis

The largest muscle in the quadriceps femoris that is responsible for extending and stabilizing the knee.

VASP wt Allele

Human VASP wild-type allele is located in the vicinity of 19q13.32 and is approximately 20 kb in length. This allele, which encodes…

VASP Gene

This gene is involved in both cell adhesion and motility.

Vasovagal Syncope

Loss of consciousness due to a reduction in blood pressure that is associated with an increase in vagal tone and peripheral…

Vasovagal Reaction

Sudden drop of the blood pressure, bradycardia, and peripheral vasodilation that may lead to loss of consciousness. It results from an increase…

Vasovagal

Relating to the action of the vagus nerve upon the blood vessels.