VB4-845

A substance being studied in the treatment of certain types of head and neck cancer. VB4-845 is made by linking a monoclonal antibody fragment to a toxic protein that may kill cancer cells. It binds to EpCAM (a protein on the surface of epithelial cells and some types of cancer cells). Also called anti-EpCAM-Pseudomonas-exotoxin fusion protein and Proxinium. (NCI Dictionary)

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Human VAV3 wild type allele is located in the vicinity of 1p13.3 and is approximately 394 kb in length. This allele, which…

VAV3 Protein

Encoded by human VAV3 Gene (VAV Family), the 847-amino acid VAV-3 Protein exhibits similarity to VAV1 and VAV2. Alpha and beta isoforms…

VAV3 Gene

This gene plays a role in signal transduction and modulation of cell morphology. It is also involved in the regulation of platelet…

VAV2 wt Allele

Human VAV2 wild type allele is located in the vicinity of 9q34.1 and is approximately 231 kb in length. This allele, which…

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A member of the VAV oncogene family, VAV2 is a probable exchange factor for a RAS-like GTP-binding protein and responds to a…

VAV2 Gene

This gene plays a role in signal transduction and negative regulation of T-cell activation.