VCL-CB01 Vaccine

A vaccine consisting of two plasmids encoding the human cytomegalovirus (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with immunostimulatory properties. Vaccination with VCL-CB01 may stimulate the host immune system to mount cellular and humoral immune responses against CMV positive cells, resulting in cell lysis. (NCI Thesaurus)

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VCL wt Allele

Human VCL wild-type allele is located within 10q22.1-q23 and is approximately 122 kb in length. This allele, which encodes vinculin protein, is…

VCL Gene

This gene plays a role in cytoskeletal regulation and cellular adhesion.

VCAN wt Allele

Human VCAN wild-type allele is located in the vicinity of 5q14.3 and is approximately 111 kb in length. This allele, which encodes…

VCAN Gene

This gene is involved in both cell adhesion and proteoglycan metabolism.

VCAM1 wt Allele

Human VCAM1 wild-type allele is located within 1p32-p31 and is approximately 19 kb in length. This allele, which encodes vascular cell adhesion…

VCAM1 Gene

This gene is involved in the regulation of leukocyte-endothelial cell adhesion interactions.