| Health / Medical Topics |
Vinepidine
A vinca alkaloid compound and semi-synthetic vincristine derivative with antineoplastic activity. Vinepidine binds to and stabilizes tubulin, thereby preventing tubulin polymerization and depolymerization, which result in microtubule assembly and disassembly, respectively. Treated cells are unable to complete mitosis process and are arrested in the metaphase, thereby leading to an inhibition of cell growth. (NCI Thesaurus)
YOU MAY ALSO LIKE
An instrument for evaluation of social functioning in individuals from preschool to 18 years old. Focusing on adaptive behaviors, the results are…
An indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
The sulfate salt form of Vindesine. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of…
An anticancer drug that belongs to the family of plant drugs called vinca alkaloids.
Encoded by a single human tumor suppressor VCL Gene, Vinculin contains 1,066 amino acids with strong similarity to other vinculins and…
A regimen containing vincristine, dactinomycin and cyclophosphamide used for the treatment of intermediate-risk childhood rhabdomyosarcoma.
