| Health / Medical Topics |
Vitaxin-2
A modified version of Vitaxin, a humanized monoclonal IgG1 antibody to alpha(v)beta(3)integrin. Exhibiting improved affinity to alpha(v)beta(3)integrin compared to first-generation Vitaxin, Vitaxin-2 blocks the binding of ligands, such as vitronectin, to alpha(v)beta(3) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI Thesaurus)
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