Health / Medical Topics

    Vitronectin

    Definition 1

    This protein is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. (NCI Thesaurus/LocusLink)

    Definition 2

    A blood plasma glycoprotein that mediates cell adhesion and interacts with proteins of the complement, coagulation, and fibrinolytic cascade. (From Segen, Dictionary of Modern Medicine, 1992) (NLM, Medical Subject Headings)

    Definition 3

    fibronectin-like extracellular glycoprotein involved in cell adhesion. (NIH CRISP Thesaurus)




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