Health / Medical Topics

    VWF wt Allele

    Human VWF wild-type allele is located in the vicinity of 12p13.3 and is approximately 176 kb in length. This allele, which encodes Von Willebrand factor protein, plays a role in factor transport, platelet-vessel wall mediation, and coagulation. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. (NCI Thesaurus)




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