| Health / Medical Topics |
WNT1 Inducible Signaling Pathway Protein 2
Encoded by human oncogene WISP2 Gene, the 250-amino acid WNT1 Inducible Signaling Pathway Protein 2 constitutes - with WISP1 and WISP3 - one of three factors downstream in the WNT signaling pathway relevant to malignant transformation. WISP2 expression is reduced in 79% of human colon tumors; WISP1 and WISP3 are over expressed in colon tumors. (OMIM, Swiss-Prot, LocusLink, and NCI) (NCI Thesaurus)
YOU MAY ALSO LIKE
Associated with cell survival and expressed in fibroblasts (high), heart, kidney, lung, pancreas, placenta, ovary, small intestine, and spleen by human WISP1…
This gene plays a role in signal transduction and intercellular communication. It is involved in neural development.
Wnt glycoproteins play a role in diverse processes during embryonic patterning in metazoa through interaction with frizzled-type seven-transmembrane-domain receptors (Frz) to stabilize…
A formylated, six amino acid, Wnt5a-derived peptide and wnt-5a mimetic with potential anti-metastatic activity. Upon intravenous administration, Wnt-5a mimic hexapeptide foxy-5 binds…
Encoded by human WNT3 Gene (WNT Family), 355-amino acid 39.6 kD (precursor) WNT-3 Protein is a wingless (Drosophila) homolog with 98% amino…
Encoded by human WNT10B Gene (WNT Family), 389-amino acid 43 kD (precursor) WNT-10B Protein is expressed in most adult tissues; heart and…
