Health / Medical Topics

    WT1-AS wt Allele

    Human WT1-AS wild-type allele is located in the vicinity of 11p13 and is approximately 23 kb in length. This allele, which encodes Wilms tumor-associated antisense RNA, may be involved in the regulation of WT1 gene expression. This gene is imprinted in the kidney, displays preferential expression from the paternal allele, and imprinting defects at chromosome 11p13 may be associated with Wilms tumor. (NCI Thesaurus)




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