X-Chromosome Inactivation

A human early embryonic event in which in any given cell one of a female's two X chromosomes becomes inactivated and converted into a Barr body. After inactivation has occurred, all descendants of that cell have the same inactivated X chromosome. Thus, X-inactivation creates cell clones with differing effective gene content. An organism whose cells vary in effective gene content and hence in the expression of a trait, is called a genetic mosaic. (NCI Thesaurus)

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An open source scoring engine from The Global Proteome Machine Organization that can match tandem mass spectra with peptide sequences.

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This gene is involved in regulation of transcription. It is involved in fetal/neonatal cardiac and muscle development.

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Human WWP2 wild-type allele is located in the vicinity of 16q22.1 and is approximately 179 kb in length. This allele, which encodes…