Z-360

A selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the proliferation of gastrointestinal and pancreatic tumor cells. (NCI Thesaurus)

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Z Isomer

A double bond with its highest priority side groups on the same sides.

YY1 wt Allele

Human YY1 wild-type allele is located within 14q and is approximately 44 kb in length. This allele, which encodes transcriptional repressor protein…

YY1 Gene

This gene is involved in the negative regulation of transcription.

YXXP Motif

YXXP (tyrosine-X-X-Proline), a substrate sequence preferred by Abl tyrosine kinases, is part of the SH2 domain that mediates certain interactions of SH2…

YWHAZ wt Allele

Human YWHAZ wild-type allele is located in the vicinity of 8q23.1 and is approximately 35 kb in length. This allele, which encodes…

YWHAZ Gene

This gene is involved in both interactions with phosphoproteins and signal transduction.