Zibotentan

Pronunciation

Definition 1

A substance being studied in the treatment of some types of cancer. Zibotentan may block cancer cell growth. It is a type of endothelin-A receptor antagonist. (NCI Dictionary)

Definition 2

An orally available selective antagonist of the endothelin-A (ET-A) receptor with potential antineoplastic activity. Zibotentan binds selectively to the ET-A receptor, thereby inhibiting endothelin-mediated mechanisms that promote tumor cell proliferation. (NCI Thesaurus)

Definition 3

A substance that is being studied in the treatment of prostate cancer. It belongs to the family of drugs called endothelin-receptor antagonists. (NCI Dictionary)

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