Health / Medical Topics |
ZIC1 wt Allele
Human ZIC1 wild-type allele is located in the vicinity of 3q24 and is approximately 7 kb in length. This allele, which encodes zinc finger protein ZIC 1, plays roles in regulation of transcription, development and differentiation of cerebellar granule cells. Mutations in this gene are associated with Dandy-Walker malformation. (NCI Thesaurus)
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