Ziconotide

Pronunciation

Definition 1

A drug used in the treatment of chronic pain. Also called Prialt and SNX 111. (NCI Dictionary)

Definition 2

A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain. (NCI Thesaurus)

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