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ADDUCT
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
A compound formed by an addition reaction
Classified under:
Hypernyms ("adduct" is a kind of...):
chemical compound; compound ((chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight)
II. (verb)
Verb forms
Present simple: I / you / we / they adduct ... he / she / it adducts
Past simple: adducted
-ing form: adducting
Sense 1
Meaning:
Example:
adduct the thigh muscle
Classified under:
Verbs of touching, hitting, tying, digging
Hypernyms (to "adduct" is one way to...):
draw; pull (cause to move by pulling)
Sentence frame:
Something ----s
Antonym:
abduct (pull away from the body)
Derivation:
adduction ((physiology) moving of a body part toward the central axis of the body)
adductive (especially of muscles; bringing together or drawing toward the midline of the body or toward an adjacent part)
adductor (a muscle that draws a body part toward the median line)
Context examples:
Nucleotide Excision Repair (NER) Inhibition involves interference with, or restraint of, the activities that mend DNA regions containing chemical adducts, carcinogenic adducts, or thymine dimers.
(Nucleotide Excision Repair Inhibition, NCI Thesaurus)
Upon intravenous administration, doxorubicin intercalates DNA, interferes with the activity of topoisomerase II, and causes DNA adducts and other DNA damage, resulting in tumor cell growth inhibition and apoptosis.
(Nanoparticle-encapsulated Doxorubicin Hydrochloride, NCI Thesaurus)
Nucleotide Excision Repair (NER) mends DNA regions that contain chemical adducts, such as UV-induced thymine dimers or carcinogenic adducts, which distort the DNA helix and interfere with replication and transcription.
(Nucleotide Excision Repair, NCI Thesaurus)
Used as a topical treatment for skin hyperpigmentation and in various cosmetic products, it is metabolized mainly to glutathione conjugates and forms mutagenic DNA adducts in in-vitro systems.
(Hydroquinone, NCI Thesaurus)
The most superficial muscle extending vertically downward along the inner thigh which adducts the thigh, rotates the leg medially and flexes the knee.
(Gracilis, NCI Thesaurus)
Upon intravenous administration of a microdose of carbon C 14 oxaliplatin, the oxaliplatin moiety covalently links to DNA and forms mono- and di-DNA adducts.
(Carbon C 14 Oxaliplatin, NCI Thesaurus)
Its metabolites, via cytochrome P450 oxidation, are potent alkylating agents and causes DNA adducts, which is responsible for the carcinogenic effect.
(Bromoethene, NCI Thesaurus)
BBR 3464 binds to and forms DNA crosslinks and platinum-DNA adducts, preventing DNA replication and tumor cell division.
(BBR 3464, NCI Thesaurus)
An alkylating agent that bind to the DNA minor groove in a sequence-specific manner and form covalent adducts with adenines, resulting in the inhibition of DNA replication and induction of apoptosis.
(Adozelesin, NCI Thesaurus)
Useful in assessing for developmental dysplasia of the hip, this test is performed when the thigh is pushed posteriorly and the hip is adducted.
(Barlow's Maneuver, NCI Thesaurus)