Health / Medical Topics |
Affected
Definition 1
To be influenced by or changed. (NCI Thesaurus)
Definition 2
Individuals in a pedigree who exhibit the specific phenotype under study. (NCI Dictionary)
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Human AFF4 wild-type allele is located in the vicinity of 5q31 and is approximately 88 kb in length. This allele, which encodes…
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This gene plays a regulatory role in transcription and is involved in male germ cell differentiation.
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Human AFF3 wild-type allele is located within 2q11.2-q12 and is approximately 595 kb in length. This allele, which encodes AF4/FRM2 family member…
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This gene is involved in transcriptional activation and is purported to play roles in lymphoid development and oncogenesis.
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Human AFF1 wild-type allele is located in the vicinity of 4q21 and is approximately 206 kb in length. This allele, which encodes…
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This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia.
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