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ALPHA-ADRENERGIC RECEPTOR
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasoconstriction and relaxation of intestinal muscles and contraction of smooth muscles)
Synonyms:
alpha-adrenergic receptor; alpha-adrenoceptor; alpha receptor
Classified under:
Hypernyms ("alpha-adrenergic receptor" is a kind of...):
receptor (a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response)
Holonyms ("alpha-adrenergic receptor" is a part of...):
sympathetic nervous system (originates in the thoracic regions of the spinal cord; opposes physiological effects of the parasympathetic: reduces digestive secretions; speeds the heart; contracts blood vessels)
Context examples:
Phenylephrine hydrochloride, a direct-acting sympathicomimetic amine, activates alpha-adrenergic receptors in the nasal mucosa thereby causing vasoconstriction, reduces swelling of nasal mucous membranes and decreases nasal and sinus congestion.
(Entex, NCI Thesaurus)
Phenylephrine hydrochloride, a sympathomimetic agent, acts as a decongestant by inducing blood vessels constriction mediated via alpha-adrenergic receptors, thereby reducing blood flow and decreasing swelling which prevents nasal and sinus congestion.
(DuraVent DA, NCI Thesaurus)
Another ingredient of Dayquil, phenylephrine, a post-synaptic alpha-adrenergic receptor agonist, induces vasoconstriction, and thereby reduces blood flow, decreases swelling and prevents nasal and sinus congestion.
(Dayquil, NCI Thesaurus)
An alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.
(Dapiprazole Hydrochloride, NCI Thesaurus)
Administered in the conjunctiva, epinephrine bitartrate induces vasoconstriction and decreases the production of aqueous humor mediated through alpha-adrenergic receptors.
(Epinephrine Bitartrate, NCI Thesaurus)
By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure.
(Epinephrine Hydrochloride, NCI Thesaurus)
This agent also selectively binds to alpha-adrenergic receptors, thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins, which also contributes to the relief of headaches.
(Ergotamine, NCI Thesaurus)
Pseudoephedrine displaces norepinephrine from storage vesicles in presynaptic neurons, thereby releasing norepinephrine into the neuronal synapses where it stimulates primarily alpha-adrenergic receptors in the nasal mucosa, thereby producing vasoconstriction, reduces swelling of nasal mucous membranes and decreasing nasal and sinus congestion.
(Guaifenesin/Pseudoephedrine, NCI Thesaurus)
Pseudoephedrine displaces norepinephrine from storage vesicles in presynaptic neurons, thereby releasing norepinephrine into the neuronal synapses where it stimulates primarily alpha-adrenergic receptors in the nasal mucosa, thereby producing vasoconstriction, reduces swelling of nasal tissues and decreasing nasal and sinus congestion.
(Loratadine/Pseudoephedrine, NCI Thesaurus)
When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure.
(Epinephrine Hydrochloride, NCI Thesaurus)
