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Altretamine
Pronunciation
Definition 1
An anticancer drug that belongs to the family of drugs called alkylating agents. (NCI Dictionary)
Definition 2
A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage. (NCI Thesaurus)
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